A Study of Metabolism in Severe Diabetes

Francis G. Benedict, Elliott P. Joslin

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On the other hand, we see no reason to alter our Opinion there expressed that with diabetics the dextrose — nitrogen ratio is at best a very uncertain factor, and unless a rigidly strict carbohydrate-free diet be adhered to for several days, the dextrose — nitrogen ratios have little, if any, significance. Neither do we see any reason for changing our belief that the adherence to a strictly carbohydrate — free diet in severe diabetes during a period of several days is a procedure very much to be questioned. This being the case, the Significance of the dextrose-nitrogen ratio for diagnostic purposes has not, we believe, the importance that has been ascribed to it by other writers.

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